Whether you work from home or have a nine-to-five job, one of the most important skills you can learn is how to separate your private and professional lives.  Especially if you run your own business, the temptation to always be "on", to always be active in managing your business affairs can be overwhelming, but letting work intrude too much and too often on your private life is a good way to increase your overall stress level, risking burnout.  Being able to draw a clear line between work and home is integral to staying happy, balanced, and healthy.

These days, our jobs try to get as much out of us as they can.  All too often, leaving the office in the evening is only a symbolic separation - we remain tied to our desks through phones and email, and even if not directly contacted, we often spend our down time mulling over problems experienced during the day.  Worse, if we run our own business from home, the office is never farther than the door down the hall, and extracting ourselves from the workday can be nearly impossible.

Though it can be difficult, an important step is simply to cut the ties.  If an issue is not an emergency (and most of them aren't), it can be dealt with during normal business hours the following day.  Schedule time for yourself away from work, and when you go on vacation, make a point of not checking in regularly "to see how things are going".  The more distance you can put between yourself and your job, the better you'll be able to relax, and the happier and healthier you'll be for it.